The first and most common is single or localized lesions. Vesicles. A papule is a raised area of skin tissue that’s less than 1 centimeter around. Macular vs Papular Rash: Changes in the skin color or consistency without any elevation from the skin level are known as macules. Remember: Changes with size Changes with depth Macules patches Erosion ulcer Papules plaques (or nodules) Vesicles … It can appear in a variety of shapes, colors, and sizes. Overview. Margins of the lesion are elevated. To differentiate these skin lesions from each other, here are the pictures of each. (>10mm bulla) (herpes, varicella) Wheal or hive: A localized edematous plaque-like lesion, somewhat irregular and transient. A papule can have distinct or indistinct borders. Vesicle: Well circumscribed fluid-filled lesion up to 5-10mm. Plaque — a circumscribed, palpable lesion more than 1 cm in diameter; most plaques are elevated. Vesicles are small, fluid-filled sacs that can appear on your skin. - Anything that develops out of a papule is usually a vesicle (despite "sans bulle" in your text example). A nodule is a circumscribed elevation of the skin larger than a papule (1 cm). A papule is a raised white lesion that is essentially less than 0.5cm in diameter. - "Vesicles" and "bullae" works for an expert audience. - The technical umbrella term is usually "bullous", rather than "vesicular" dermatitis/eruptions. 10 An example is anthrax, with its evolving cutaneous lesion from painless papule to ulcer with surrounding vesicles. They often extend into the dermis, and may be due to inflammatory, neoplastic, or metabolic in origin. Plaques may result from a coalescence of papules. Cyst — papule or nodule that contains fluid or semi-fluid material so is fluctuant. Papules P. Papules are circumscribed, solid elevations of the skin, up to 1 cm in diameter. Maculopapular rash may be mistakenly called macule, papule, patch, nodule, plaque, vesicle, or pustule. -papule -plaque -nodule -tumor -vesicle -bulla -pustule -cyst Secondary Lesions -scale -crust -excoriation -lichenification -maceration -fissure -erosion -ulcer Distinct Lesions -wheal/hive -burrow -comedone -atrophy -keloid -fibrosis -petechiae -telangiectasis -milium: Papule. Vesicular lesions (Table 132.11) can be considered in three clinical categories. These include macules, papules, nodules, plaques, vesicles, bullae, pustules, and wheals. Elevation: Margins of the lesion are not elevated. The fluid inside these vesicles may be clear, white, yellow, or mixed with blood. Picture 12: Macule measures less than 1 cm. Photo from Wright State University Dermatology -papule -plaque -nodule -tumor -vesicle -bulla -pustule -cyst Secondary Lesions -scale -crust -excoriation -lichenification -maceration -fissure -erosion -ulcer Distinct Lesions -wheal/hive -burrow -comedone -atrophy -keloid -fibrosis -petechiae -telangiectasis -milium: Vesicle. It is a flat blemish like that of a freckle. Vesicles are tiny sacs that transport material within or outside the cell. There are several types of vesicle, including transport vesicles, secretory vesicles, and lysosomes.