There are several types of vesicle, including transport vesicles, secretory vesicles, and lysosomes. Cyst — papule or nodule that contains fluid or semi-fluid material so is fluctuant. (>10mm bulla) (herpes, varicella) Wheal or hive: A localized edematous plaque-like lesion, somewhat irregular and transient. Plaque — a circumscribed, palpable lesion more than 1 cm in diameter; most plaques are elevated. Vesicles. A papule can have distinct or indistinct borders. Overview. They often extend into the dermis, and may be due to inflammatory, neoplastic, or metabolic in origin. Vesicles are tiny sacs that transport material within or outside the cell. The first and most common is single or localized lesions. Vesicular lesions (Table 132.11) can be considered in three clinical categories. Margins of the lesion are elevated. Papules P. Papules are circumscribed, solid elevations of the skin, up to 1 cm in diameter. - "Vesicles" and "bullae" works for an expert audience. A papule is a raised area of skin tissue that’s less than 1 centimeter around. These include macules, papules, nodules, plaques, vesicles, bullae, pustules, and wheals. Picture 12: Macule measures less than 1 cm. 10 An example is anthrax, with its evolving cutaneous lesion from painless papule to ulcer with surrounding vesicles. -papule -plaque -nodule -tumor -vesicle -bulla -pustule -cyst Secondary Lesions -scale -crust -excoriation -lichenification -maceration -fissure -erosion -ulcer Distinct Lesions -wheal/hive -burrow -comedone -atrophy -keloid -fibrosis -petechiae -telangiectasis -milium: Papule. The fluid inside these vesicles may be clear, white, yellow, or mixed with blood. Macular vs Papular Rash: Changes in the skin color or consistency without any elevation from the skin level are known as macules. Photo from Wright State University Dermatology A nodule is a circumscribed elevation of the skin larger than a papule (1 cm). It can appear in a variety of shapes, colors, and sizes. Remember: Changes with size Changes with depth Macules patches Erosion ulcer Papules plaques (or nodules) Vesicles … - Anything that develops out of a papule is usually a vesicle (despite "sans bulle" in your text example). Vesicle: Well circumscribed fluid-filled lesion up to 5-10mm. -papule -plaque -nodule -tumor -vesicle -bulla -pustule -cyst Secondary Lesions -scale -crust -excoriation -lichenification -maceration -fissure -erosion -ulcer Distinct Lesions -wheal/hive -burrow -comedone -atrophy -keloid -fibrosis -petechiae -telangiectasis -milium: Vesicle. A papule is a raised white lesion that is essentially less than 0.5cm in diameter. Vesicles are small, fluid-filled sacs that can appear on your skin. To differentiate these skin lesions from each other, here are the pictures of each. It is a flat blemish like that of a freckle. Maculopapular rash may be mistakenly called macule, papule, patch, nodule, plaque, vesicle, or pustule. Plaques may result from a coalescence of papules. - The technical umbrella term is usually "bullous", rather than "vesicular" dermatitis/eruptions. Elevation: Margins of the lesion are not elevated.